China (Mainland)
HS-173 CAS NO.1276110-06-5
- Min.Order: 1 Gram
- Payment Terms:
- Product Details
Keywords
- HS-173
- 1276110-06-5
- 99% HS-173
Quick Details
- ProName: HS-173
- CasNo: 1276110-06-5
- Molecular Formula: C21H18N4O4S
- Application: 1276110-06-5
- DeliveryTime: in stock
- ProductionCapacity: 100g Metric Ton/Day
- Purity: 99%
- LimitNum: 1 Gram
Superiority
In stock ,If you need HNMR\HPLC,please contact us!
Details
HS-173 shows potent antiproliferative effects in T47D, SK-BR3, and MCF7 cells with IC50 of 0.6, 1.5, and 7.8 μM, respectively. HS-173 causes complete suppression of the PI3K pathway in cancer cell lines (Hep3B and SkBr3). Moreover, HS-173 induces cell apoptosis by affecting cell-cycle distribution and activating caspases, and block VEGF-induced angiogenesis in vitro. Combined treatment with Sorafenib and HS-173 has a synergistic anti-cancer effect on pancreatic cancer cells