China (Mainland)
ANA-12 CAS NO.219766-25-3
- Min.Order: 1 Gram
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- Product Details
Keywords
- ANA-12
- 219766-25-3
- 99% ANA-12
Quick Details
- ProName: ANA-12
- CasNo: 219766-25-3
- Application: 219766-25-3
- DeliveryTime: in stock
- ProductionCapacity: 100g Metric Ton/Day
- Purity: 99%
- LimitNum: 1 Gram
Superiority
In stock ,If you need HNMR\HPLC,please contact us!
excellent quality and reasonable price and absolutely worthy.
Details
ANA-12 prevented activation of the receptor by BDNF with a high potency. ANA-12 showed direct and selective binding to TrkB and inhibited processes downstream of TrkB without altering TrkA and TrkC functions. Saturation binding studies with TrkBECD-Fc showed that ANA-12 binds TrkBECD-Fc with a Kd of 12 μM . The selective TrkB (tropomyosin-receptor-kinase) antagonist ANA-12 reduced OIH when given one or seven days after cessation of morphine.