- Product Details
Keywords
- AZD1080
- 612487-72-6
- 99% AZD1080
Quick Details
- ProName: AZD1080
- CasNo: 612487-72-6
- Molecular Formula: C19H18N4O2
- Application: 612487-72-6
- DeliveryTime: in stock
- ProductionCapacity: 100g Metric Ton/Day
- Purity: 99%
- LimitNum: 1 Gram
Superiority
In stock ,If you need HNMR\HPLC,please contact us!
Details
AZD1080 inhibits tau phosphorylation in cells expressing human tau and in intact rat brain. Interestingly, subchronic but not acute administration with AZD1080 reverses MK-801-induced deficits, measured by long-term potentiation in hippocampal slices and in a cognitive test in mice, suggesting that reversal of synaptic plasticity deficits in dysfunctional systems requires longer term modifications of proteins downstream of GSK3β signaling.