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Obeticholic Acid intermediates and impurities
Obeticholic acid (6-ethylchenodeoxycholic acid, 6-ECDCA, INT-747, OCA), is a bile acid analog and first-in-class FXR agonist currently in Phase III clinical development for the treatment of primary biliary cirrhosis (PBC) and in Phase II clinical development for the treatment of Nonalcoholic steatohepatitis (NASH) and Primary Sclerosing Cholangitis (PSC).